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Curr Biol. 2019 May 6;29(9):R334-R337. doi: 10.1016/j.cub.2019.03.026.

Tissue Patterning: The Winner Takes It All, the Losers Standing Small.

Author information

1
Department of Molecular Medicine and School of Medicine, University of Padua, Padua, Italy. Electronic address: sirio.dupont@unipd.it.
2
Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, and Department of Biomedical Engineering, Viterbi School of Engineering, University of South California, Los Angeles, CA, USA. Electronic address: Leonardo.Morsut@med.usc.edu.

Abstract

A new mechanism for the selection and differentiation of a single cell, based on mechanical competition with its neighbors and differential TAZ activity, is shown to be at play during zebrafish oogenesis to prevent polyspermy.

PMID:
31063728
DOI:
10.1016/j.cub.2019.03.026

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