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Transplant Proc. 2019 Jun;51(5):1314-1316. doi: 10.1016/j.transproceed.2019.01.130. Epub 2019 May 2.

Role of Computed Tomography Volumetry in Preoperative Donor Renal Function Evaluation of Living Related Kidney Transplantation.

Author information

1
Department of Urology, Fukuoka University Hospital, Fukuoka City, Fukuoka, Japan. Electronic address: nobu0149@fukuoka-u.ac.jp.
2
Department of Urology, Fukuoka University Hospital, Fukuoka City, Fukuoka, Japan.

Abstract

INTRODUCTION:

Renal scintigraphy is used to evaluate split renal function. A computed tomography (CT) examination is also carried out for donor safety and appropriate transplantation surgery, and the renal volume (CT volumetry) can be obtained at that time. In this study, we evaluated donor kidney function by inulin clearance (Cin) before and after donor nephrectomy in living donor renal transplantation, and the predictive role of CT volumetry was compared with diethylenetriamine pentaacetic acid (DTPA).

METHOD:

From November 2005 to April 2018, 34 cases of living donor transplantation conducted at Fukuoka University Hospital were retrospectively studied. The donated kidney weight was measured in 25 cases, and postoperative Cin was measured in 19 cases.

RESULTS:

The average donor age was 51.7 years old (from 35 to 71). Preoperative Cin and postoperative Cin of donors were 86.3 mL/min/1.73 m2 (from 59.5 to 138.3) and 52.3 (from 40.5 to 76.6), respectively. The average CT volumetry of donated kidneys was 153.9 mL (from 107.8 to 219.3). Correlations of weight and DTPA and CT volumetry of donated kidneys were r = 0.033 (P = .8770) and r = 0.763 (P < .0001), respectively. Correlations of glomerular filtration rate of DTPA and CT volumetry and Cin of postoperative donor residual kidneys were r = 0.66 (P = .002) and r = 0.555 (P = .014).

CONCLUSION:

There was a significant correlation between CT volumetry and the weight of the removed kidneys, and a correlation between Cin after donor nephrectomy and CT volumetry of the remaining kidneys, but it did not exceed the predictive role of DTPA. However, it was suggested that it is worthy to use as a preoperative examination for split renal function equivalent to DTPA.

[Indexed for MEDLINE]

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