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Biochim Biophys Acta. 1987 Apr 22;928(2):240-2.

Epidermal growth factor actions on arachidonic acid metabolism in human amnion cells.

Abstract

Epidermal growth factor (EGF) from human and murine sources increased prostaglandin E2 production by human amnion cells. An anti-EGF receptor monoclonal antibody abolished this stimulatory action of EGF and reduced the basal rate of amnion prostaglandin E2 biosynthesis. The rates of formation of arachidonate lipoxygenase products were also enhanced by EGF.

PMID:
3105596
DOI:
10.1016/0167-4889(87)90127-3
[Indexed for MEDLINE]

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