Format

Send to

Choose Destination
Environ Res. 2019 Apr 25;174:88-94. doi: 10.1016/j.envres.2019.04.021. [Epub ahead of print]

Exposure to fine particles increases blood pressure of hypertensive outdoor workers: A panel study.

Author information

1
Divisao de Pneumologia do Instituto do Coraçao (InCor) Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo. Avenida Dr. Enéas Carvalho de Aguiar, 44, 8 Andar, Jardim Paulista, CEP 05403-000, Sao Paulo, SP, Brazil. Electronic address: pneubiratan@incor.usp.br.
2
Environmental Epidemiology Study Group, Laboratory of Experimental Air Pollution, Departamento de Patologia, Faculdade de Medicina, Universidade de São Paulo. Avenida Dr. Arnaldo, 455, 1 Andar sala 1304, Cerqueira César, CEP 01246-903, Sao Paulo, SP, Brazil; Environmental Exposure and Risk Assessment Group, Collective Health Post-Graduation Program, Catholic University of Santos. Avenida Conselheiro Nébias, 300, Vila Mathias, CEP 11015-002, Santos, SP, Brazil.
3
Departamento de Medicina Interna, Faculdade de Medicina, Universidade de Sao Paulo. Avenida Dr. Arnaldo, 455, 1 Andar, Cerqueira César, CEP 01246-903, São Paulo, SP, Brazil.
4
Environmental Epidemiology Study Group, Laboratory of Experimental Air Pollution, Departamento de Patologia, Faculdade de Medicina, Universidade de São Paulo. Avenida Dr. Arnaldo, 455, 1 Andar sala 1304, Cerqueira César, CEP 01246-903, Sao Paulo, SP, Brazil; Departamento de Medicina Interna, Faculdade de Medicina, Universidade de Sao Paulo. Avenida Dr. Arnaldo, 455, 1 Andar, Cerqueira César, CEP 01246-903, São Paulo, SP, Brazil.
5
Environmental Epidemiology Study Group, Laboratory of Experimental Air Pollution, Departamento de Patologia, Faculdade de Medicina, Universidade de São Paulo. Avenida Dr. Arnaldo, 455, 1 Andar sala 1304, Cerqueira César, CEP 01246-903, Sao Paulo, SP, Brazil.
6
Instituto de Matemática e Estatística, Universidade de São Paulo. Rua do Matão, 1010, Butantã, CEP 05508-090, São Paulo, SP, Brazil.
7
Environmental Epidemiology Study Group, Laboratory of Experimental Air Pollution, Departamento de Patologia, Faculdade de Medicina, Universidade de São Paulo. Avenida Dr. Arnaldo, 455, 1 Andar sala 1304, Cerqueira César, CEP 01246-903, Sao Paulo, SP, Brazil; Instituto de Estudos Avançados da Universidade de São Paulo. Rua do Anfiteatro, 513, Butantã, CEP 05508-060, São Paulo, SP, Brazil.

Abstract

BACKGROUND:

Hypertension and air pollution are two important risk factors for cardiovascular morbidity and mortality. Although several studies suggest that air pollution has a significant impact on blood pressure, studies on long-term effects are sparse and still controversial.

OBJECTIVE:

To evaluate the effects of exposure of outdoor workers to different levels of traffic-generated PM2.5 on blood pressure.

DESIGN:

This is an observational panel study.

PARTICIPANTS:

88 non-smoking workers exposed to different concentrations of air pollution were evaluated weekly along four successive weeks.

MEASUREMENTS:

In each week, personal monitoring of 24-h PM2.5 concentration and 24-h ambulatory blood pressure were measured. The association between blood pressure variables and PM2.5, adjusted for age, body mass index, time in job, daily work hours, diabetes, hypertension and cholesterol was assessed by means of multiple linear regression models fitted by least squares.

RESULTS:

Exposure to PM2.5 (ranging from 8.5 to 89.7 μg/m3) is significantly and consistently associated with an increase in average blood pressure. An elevation of 10 μg/m3 in the concentration of PM2.5 is associated with increments of 3.9 mm Hg (CI 95% = [1.5; 6.3]) in average systolic 24-h blood pressure for hypertensive and/or diabetic workers.

CONCLUSION:

Exposure to fine particles, predominantly from vehicular traffic, is associated with elevated blood pressure in hypertensive and/or diabetic workers.

KEYWORDS:

Air pollution; Blood pressure; Panel study; Personal monitor; Vehicular air pollution

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center