Format

Send to

Choose Destination
Cell Stem Cell. 2019 May 2;24(5):685-687. doi: 10.1016/j.stem.2019.04.010.

Lessons from London and Berlin: Designing A Scalable Gene Therapy Approach for HIV Cure.

Author information

1
Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA; Department of Medicine, University of Washington, Seattle, WA 98195, USA.
2
Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA; Department of Medicine, University of Washington, Seattle, WA 98195, USA; Department of Pathology, University of Washington, Seattle, WA 98195, USA; Washington National Primate Research Center, Seattle, WA 98195, USA. Electronic address: hkiem@fhcrc.org.

Abstract

Recently in Nature, Gupta et al. (2019) reported that a second patient has achieved HIV-1 remission/functional cure after allogeneic hematopoietic stem cell transplantation from a donor carrying a mutation in the CCR5 coreceptor. We highlight both patients' treatments and summarize efforts to develop a broader, more patient-friendly approach.

PMID:
31051132
DOI:
10.1016/j.stem.2019.04.010

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center