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Skin Appendage Disord. 2019 Apr;5(3):146-151. doi: 10.1159/000493200. Epub 2018 Oct 10.

Effects of a New Topical Treatment Containing Several Hair Growth Promoters in Women with Early Female Pattern Hair Loss.

Author information

1
Private Hospital Nigrisoli, Bologna, Italy.
2
Leonard M. Miller School of Medicine, University of Miami, Miami, Florida, USA.
3
Private Consultant, Boca Raton, Florida, USA.

Abstract

Background:

Female pattern hair loss (FPHL) is increasing ly common and often presents with hair shedding. Spec tral. DNC-N® contains anti-inflammatory actives and hair growth promoters.

Objectives:

To assess the efficacy and tolerability of Spectral DNC-N® (DS Laboratories, Inc.) in women with early FPHL and excessive shedding.

Methods:

Forty-nine patients were treated with Spectral DNC-N®, applied twice daily for 3 months; 28 patients were included in the 3-month treatment extension. Efficacy assessments included the degree of hair shedding using the validated hair shedding visual scale, hair mass index (HMI), and photographic evaluation.

Results:

There was a statistically significant decrease in hair shedding and a corresponding increase in HMI by month 3, which was maintained through month 6. The mean investigator-assessed hair shedding score decreased from 3.5 to 2.0 and the hair mass increased from 75.8 to 84.3 mm>sup<2>/sup</cm>sup<2>/sup< by month 3 (both p < 0.01 compared with baseline). By month 6, the hair shedding score was reduced to 1.6 and the hair mass was maintained. Most patients (75%) showed an increase in global hair density.

Conclusions:

Spectral. DNC-N® significantly reduced hair shedding, with a corresponding increase in hair mass and density. These effects were already evident after 3 months' treatment and further improved in those patients who continued treatment to month 6. Tolerability was good and patient satisfaction levels were high.

KEYWORDS:

Female pattern hair loss; Global photography; Hair growth promoters; Hair mass index; Hair shedding visual scale; Spectral. DNC-N®

PMID:
31049335
PMCID:
PMC6489052
[Available on 2020-04-01]
DOI:
10.1159/000493200
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