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Mutat Res. 1987 Apr;187(4):219-22.

Bio-antimutagenic effect of L-cysteine on diiodohydroxyquinoline-induced micronuclei in Swiss mice.


The mutagenic potential of diiodohydroxyquinoline (DIHQ), a common anti-amebic drug, was tested using the in vivo micronucleus test in Swiss mice following oral administration. It was found to be mutagenic in a dose-dependent manner. Using the same model system, the bio-antimutagenic effect of the sulfhydryl compound L-cysteine against DIHQ was established.

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