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Technol Health Care. 2019;27(S1):273-285. doi: 10.3233/THC-199026.

Experimental study on healthy volunteers based on magnetic induction brain edema monitoring system.

Xu J1,1, Li G2,1, Zhao S1, Chen M1, Chen J1, Xu L1, Wang F1, Bai Z1, Qin M1, Sun J1,3.

Author information

1
College of Biomedical Engineering, Third Military Medical University, Chongqing 400038, China.
2
School of Electrical and Electronic Engineering, Chongqing University of Technology, Chongqing 400000, China.
3
Department of Neurosurgery, Southwest Hospital, Chongqing 400038, China.

Abstract

BACKGROUND:

Cerebral edema is a common secondary disease after stroke. It is very important to realize real-time continuous monitoring of cerebral edema for stroke patients.

OBJECTIVE:

A non-contact magnetic induction phase shift (MIPS) detection system is used to monitor the change of global brain electrical conductivity during cerebral edema.

METHODS:

In order to verify the feasibility of this system monitoring, we carry out salt solution simulation experiments and healthy people breath holding experiments. As a comparison of later clinical experiments, 13 young healthy volunteers aged 22-35 are selected for this study to carry out a 10 minute/time monitoring experiment.

RESULTS:

It is found that the MIPS values measured by the salt solution of edema and the salt solution of bleeding are significantly different. The results show that the MIPS value of healthy young people is in a stable state with an MIPS mean value of 1.106 (± 0.736)∘. Compare it with the monitoring results of a cerebral edema patient. The MIPS of patient fluctuates greatly, and the changes of MIPS and intracranial pressure show consistent trend at the peak of the edema period.

CONCLUSIONS:

We preliminarily verify that the system can be used for cerebral edema monitoring.

KEYWORDS:

Magnetic induction phase shift; cerebral edema; healthy volunteer; intracranial pressure

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