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J Cardiovasc Electrophysiol. 2019 May 1. doi: 10.1111/jce.13957. [Epub ahead of print]

A left atrial appendage closure combined procedure review: Past, present, and future perspectives.

Author information

1
Heart Rhythm Center is the Department name; IRCCS, Centro Cardiologico Monzino is the name of the hospital, Milano, Italy.
2
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

Abstract

BACKGROUND AND OBJECTIVE:

Atrial fibrillation (AF) represents the most common cardiac arrhythmia worldwide; it poses a great burden in terms of quality of life reduction and yearly stroke risk. Left atrial appendage closure (LAAC) is a stroke prevention strategy that has been proven a viable alternative to antithrombotic regimens in nonvalvular AF patients. LAAC can be performed as a standalone procedure or alongside a concomitant AF transcatheter ablation, in a procedure known as "Combined procedure". Aim of this study is to summarize the scientific evidence backing this combined strategy.

METHODS:

We reviewed the whole Medline indexed combined procedure literature, to summarize all the combined procedure study data.

RESULTS:

Nine published studies regarding combined procedure were found. Data, aims, and scientific rationales were reported and commented.

CONCLUSION:

LAA combined procedure appears to be a safe and effective procedure; a careful patient selection is necessary to maximize its benefit.

KEYWORDS:

atrial fibrillation; catheter ablation; combined ablation; left atrial appendage; left atrial appendage closure; review; stroke prevention

PMID:
31042321
DOI:
10.1111/jce.13957

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