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Med Sci (Paris). 2019 Apr;35(4):309-315. doi: 10.1051/medsci/2019068. Epub 2019 Apr 30.

[Gene editing in drug discovery and therapeutic innovation].

[Article in French]

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Biotechnologie et signalisation cellulaire, CNRS-Unistra UMR 7242; École supérieure de biotechnologie de Strasbourg, 300, boulevard Sébastien Brant, 67412 Illkirch, France.


The idea according to which the most recent therapeutic methods will overcome the more traditional pharmacopoeia is widespread in recent publications. Biomedicine and gene therapies are booming, but we realize, as for other therapeutic approaches, that they suffer intrinsic constraints and limitations and that their most relevant therapeutic fields are complementary to those of traditional drugs. They are now viewed as potentially synergistic with these traditional drugs, rather than competitors. This review puts into perspective the potential of genome editing in the field of drug discovery and therapeutic innovation.


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