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Saudi J Kidney Dis Transpl. 2019 Mar-Apr;30(2):545-548. doi: 10.4103/1319-2442.256866.

Regression of renal angiomyolipomas with oral rapamycin therapy in a patient with tuberous sclerosis complex disease.

Author information

1
Department of Nephrology, Adana Dr. Turgut Noyan Research and Medical Center, Faculty of Medicine, Baskent University, Adana, Turkey.
2
Department of Interventional Radiology, Adana Dr. Turgut Noyan Research and Medical Center, Faculty of Medicine, Baskent University, Adana, Turkey.

Abstract

We present a case of a 32-year-old female who had been diagnosed tuberous sclerosis complex (TSC) two years ago. In view of serious hemorrhagic complication risk of the selective embolization, we commenced her on oral rapamycin therapy for regression of angiomyolipomas (AMLs). On the 1st year of rapamycin treatment, bilateral renal AMLs were regressed and bilateral selective embolization of the AML was performed after the 1st year of treatment. Rapamycin therapy may regress renal lesions in TSC disease. Therefore, it may increase surgical intervention.

PMID:
31031395
DOI:
10.4103/1319-2442.256866
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