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Lung India. 2019 May-Jun;36(3):216-225. doi: 10.4103/lungindia.lungindia_497_18.

Pneumococcal disease burden from an Indian perspective: Need for its prevention in pulmonology practice.

Author information

1
Department of Internal & Pulmonary Medicine, SKIMS Hospital, Srinagar, Jammu and Kashmir, India.
2
Department of T.B. & Chest, Dr. Murari Lal Chest Hospital, GVSM Medical College, Kanpur, Uttar Pradesh, India.
3
Department of Pulmonary, Critical Care & Sleep Medicine, Norvic International Hospital, Kathmandu, Nepal.
4
Department of Pulmonary Medicine, Christian Medical College Hospital, Vellore, Tamil Nadu, India.
5
Department of Respiratory Medicine, Fortis Hospital, Kolkata, West Bengal, India.
6
Department of Pulmonary Medicine, Dr. Kumar Doshi Clinic, Kolkata, West Bengal, India.
7
Department of Pulmonary Medicine, National Allergy Asthma Bronchitis Institute, Kolkata, West Bengal, India.
8
Department of T.B. & Chest, Geetanjali Medicity, Eklingpura, Rajasthan, India.
9
Department of Chest Medicine, Hinduja Hospital, Mumbai, Maharashtra, India.
10
Department of Pulmonary, Critical Care and Sleep Medicine, Apollo Speciality Hospital, Mumbai, Maharashtra, India.
11
Department of Chest Medicine, Bombay Hospital, Mumbai, Maharashtra, India.
12
Department of Medicine, Anwer Khan Modern Medical College, Dhaka, Bangladesh.
13
Respiratory, Critical Care & Sleep Medicine, Getwell Hospital, Nagpur, Maharashtra, India.

Abstract

Globally, pneumococcal diseases are a significant public health concern. They are preventable and frequently occur among older adults. Major risk factors for the disease are extremes of age, alcohol intake, smoking, air pollution, and comorbid conditions (diabetes, chronic obstructive pulmonary disease, chronic kidney disease, liver disease, and heart disease). Risk factors, coupled with limited disease-burden data and the emergence of antibiotics resistance, are hindering the effective management of the disease in older adults. Various global guidelines recommend pneumococcal vaccines for the prevention of pneumococcal diseases, as they reduce disease burden, hospitalization, and mortality rates among patients with comorbid conditions. Besides being an integral part of childhood immunization, these vaccines are advocated by various Indian healthcare bodies/groups for older and younger adults with certain medical conditions. The article presents an overview of the closed-door discussion by the Indian pulmonary experts on the scientific evidence and clinical practice followed for the prevention of pneumococcal disease in India.

KEYWORDS:

Chronic obstructive pulmonary disease; Streptococcus pneumoniae; community-acquired pneumonia; comorbidity; mortality; pneumococcal conjugate vaccine

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