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J Minim Access Surg. 2019 Apr 24. doi: 10.4103/jmas.JMAS_269_18. [Epub ahead of print]

Short- and long-term results after laparoscopic floppy Nissen fundoplication in elderly versus non-elderly patients.

Author information

1
Department of Surgery, University of L'Aquila, L'Aquila, Italy.
2
Department of Surgery, Hospital SS. Trinità, Sora, Italy.

Abstract

Background:

Laparoscopic anti-reflux surgery could be of benefit in a subset of elderly patients with gastroesophageal reflux disease. However, there are few reports that have evaluated the long-term results. This study examined the effects of age on the short- and long-term (for at least 5 years) outcomes after laparoscopic Nissen fundoplication (LNF).

Patients and Methods:

Patients were divided into four groups as follows: young (18-49); adult (50-69); and elderly (70-84), and very elderly (85-91). The database (recorded prospectively) included operating duration, conversion, intra- and early post-operative complication and late outcomes. Mean follow-up was 14.5 years (range 5-24 years).

Results:

Five hundred and sixty-nine patients met the inclusion criteria: young n = 219 (38.4%); adult n = 248 (43.5%); elderly n = 91 (16.0%) and very elderly n = 11 (1.9%). Hiatal hernia (type I and III) was significantly less frequent in young and adult patients (P < 0.0001). The operation was significantly longer in elderly and very elderly patients (P < 0.001); the use of drains (P < 0.001) and grafts (P < 0.0001) for hiatal hernia repair was less in young and adult patients. The hospital stay, conversion (5.4%), intra-operative and early post-operative complications were not influenced by age. Dysphagia was evenly distributed among the groups. Forty-eight (8.4%) patients had recurrence: 15 in the young group (6.8%), 18 in the adult group (7.2%), 11 in the elderly group (12%) and 4 in the very elderly group (36.3%) (P < 0.0001).

Conclusions:

Age does not influence short- and long-term outcomes following LNF. Control of reflux in the elderly is worse than adult patients. Therefore, ageing is a relative contraindication to LNF.

KEYWORDS:

Elderly; follow-up; gastroesophageal reflux disease; laparoscopic Nissen fundoplication

PMID:
31031314
DOI:
10.4103/jmas.JMAS_269_18
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