Familial properdin deficiency and fatal meningococcemia. Correction of the bactericidal defect by vaccination

N Engl J Med. 1987 Apr 9;316(15):922-6. doi: 10.1056/NEJM198704093161506.
No abstract available

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Bacterial Vaccines*
  • Blood Bactericidal Activity
  • Complement C3 / metabolism
  • Complement Pathway, Alternative
  • Complement Pathway, Classical
  • Female
  • Humans
  • Male
  • Meningococcal Infections / immunology
  • Meningococcal Infections / prevention & control*
  • Neisseria meningitidis / immunology
  • Properdin / deficiency*
  • Vaccination

Substances

  • Bacterial Vaccines
  • Complement C3
  • Properdin