Format

Send to

Choose Destination
Lasers Med Sci. 2019 Apr 26. doi: 10.1007/s10103-019-02788-3. [Epub ahead of print]

Early intervention with pulse dye and CO2 ablative fractional lasers to improve cutaneous scarring post-lumpectomy: a randomized controlled trial on the impact of intervention on final cosmesis.

Author information

1
Department of Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
2
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
3
Department of Dermatology, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, Tel Aviv, Israel.
4
Department of Reconstructive and Plastic Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
5
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. ofira@tlvmc.gov.il.
6
Department of Dermatology, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, Tel Aviv, Israel. ofira@tlvmc.gov.il.

Abstract

Light-based modalities appear to be effective for ameliorating surgical scar appearance; however, protocols for achieving such outcomes have yet to be established. We studied the safety and efficacy of a combination of pulsed dye laser (PDL) and fractional ablative CO2 laser (FACL) for the attenuation of post-lumpectomy scarring. We conducted a prospective, evaluator-blinded, comparative split-scar study in post-lumpectomy patients. One-half of the scar was treated with three sessions of 595-nm PDL and FACL at 1-month intervals, starting within 6 weeks after suture removal. The entire scar was also treated with standard moisturizers and silicone gels. Six months after the last treatment, the two halves of the scar were assessed by three uninvolved physicians who used the Observer Scar Assessment Scale as well as by the patients who used the Patient and Observer Scar Assessment Scale. Eighteen female patients (mean age, 51.3 years) with a mean scar length of 7.8 cm completed the treatment and follow-up. Six months after the last treatment, both the physician evaluators and the patients noted significant improvements for all assessed scar parameters in the laser-treated scar area compared with the untreated scar area. The treatment was well tolerated, and no remarkable adverse events were reported. All 18 participants were satisfied with the treated scar areas. A combination PDL and FACL protocol starting up to 6 weeks after suture removal is a safe and effective method for the attenuation of post-lumpectomy scar formation.

KEYWORDS:

Fractional ablative carbon dioxide laser; Lumpectomy; Patient and Observer Scar Assessment Scale; Pulsed dye laser; Scar

PMID:
31025209
DOI:
10.1007/s10103-019-02788-3

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center