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Eur J Ophthalmol. 2019 Apr 25:1120672119846437. doi: 10.1177/1120672119846437. [Epub ahead of print]

Subretinal pseudocyst: A novel optical coherence tomography finding in age-related macular degeneration.

Author information

1
1 Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy.
2
2 Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USA.
3
3 Department of Ophthalmology, Wilmer Eye Institute, School of Medicine, The Johns Hopkins University, Baltimore, MD, USA.

Abstract

PURPOSE:

To report the presence of a new structural optical coherence tomography finding, namely, subretinal pseudocysts, in a patient affected by age-related macular degeneration.

METHODS:

Case report including multimodal imaging discussion.

CASE REPORT:

We report a case of a 77-year-old woman affected by age-related macular degeneration from 7 years. Best corrected visual acuity was counting fingers and 20/40 in the right and left eye, respectively. The left eye was affected by type 1 macular neovascularization treated by 34 intravitreal injections of anti-vascular endothelial growth factor (22 ranibizumab and 12 aflibercept injections). Interestingly, structural optical coherence tomography showed the persistence of a subretinal cystoid space (i.e. 'subretinal pseudocyst') after the last anti-vascular endothelial growth factor treatment, even in absence of other signs of exudation.

CONCLUSIONS:

Subretinal pseudocysts are a new structural optical coherence tomography entity. We reported for the first time the evidence that pseudocysts may develop in the subretinal space in a case of age-related macular degeneration.

KEYWORDS:

Age-related macular degeneration; cystoid macular edema; optical coherence tomography; optical coherence tomography angiography; subretinal pseudocyst

PMID:
31018677
DOI:
10.1177/1120672119846437

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