Format

Send to

Choose Destination
J Pediatr Nurs. 2019 Jul - Aug;47:18-22. doi: 10.1016/j.pedn.2019.04.011. Epub 2019 Apr 18.

Adherence to Nutritional Supplementation in Cystic Fibrosis.

Author information

1
Center for Adherence and Self-Management, OH, United States of America; Cincinnati Children's Hospital Medical Center, OH, United States of America; University of Cincinnati College of Medicine, OH, United States of America. Electronic address: kevin.hommel@cchmc.org.
2
Nationwide Children's Hospital, OH, United States of America; Ohio State University, OH, United States of America.
3
Wayne State University School of Medicine, MI, United States of America.
4
Children's Hospital of Philadelphia, PA, United States of America.
5
Children's Hospital of Philadelphia, PA, United States of America; University of Pennsylvania Perelman School of Medicine, PA, United States of America.

Abstract

PURPOSE:

The purpose of this study was to examine patterns of adherence to a novel dietary supplement in pediatric cystic fibrosis. Adherence to dietary supplementation in cystic fibrosis is challenging, and examination of patterns of adherence behavior over time is needed to better characterize subgroups of patients who need self-management support.

DESIGN AND METHODS:

We prospectively examined adherence to Lym-X-Sorb™ (LXS), an organized lipid matrix dietary supplementation for patients with cystic fibrosis (CF) and pancreatic insufficiency (PI), over a 12-month period. Adherence for participants aged 5-17 years with CF and PI (N = 109) was monitored monthly via supplement packet counts. Group-based trajectory modeling was employed to examine patterns in adherence behavior over time.

RESULTS:

Four distinct trajectories best characterized adherence in this sample, with 18% of participants demonstrating near perfect adherence, 42% demonstrating good adherence (at or above 80%), 16% demonstrating poor adherence that declined over time, and 24% demonstrating significant non-adherence (< 30%).

CONCLUSIONS:

Some patients with CF and PI who are prescribed nutritional supplements will require intensive, individualized behavioral intervention to enhance adherence. Identifying patients who will have difficulty adhering to dietary interventions may result in better treatment-to-patient matching and improved adherence promotion efforts.

PRACTICE IMPLICATIONS:

Assessment of adherence to dietary supplementation over time can identify patients at risk for continued difficulty with self-management and provide opportunities for early intervention.

KEYWORDS:

Adherence; Cystic fibrosis; Dietary

PMID:
31005801
PMCID:
PMC6642833
[Available on 2020-07-01]
DOI:
10.1016/j.pedn.2019.04.011

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center