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J Orthod Sci. 2019 Feb 20;8:5. doi: 10.4103/jos.JOS_93_18. eCollection 2019.

45S5 Bioglass paste is capable of protecting the enamel surrounding orthodontic brackets against erosive challenge.

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Department of Orthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Orthodontics Alexandria University, Alexandria, Egypt.
Department of Operative Dentistry, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
Conservative Dentistry Department, Faculty of Dentistry, Alexandria University, Egypt.
Department of Dental Health, Jeddah Medical Center, Ministry of Defense, Jeddah, Saudi Arabia.
Department of Dental Health, Jeddah Speciality Dental Center, Ministry of Health, Jeddah, Saudi Arabia.
Faculty of Dentistry, Batterjee Medical Collage, Jeddah, Saudi Arabia.
Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.



This study aimed at evaluating the effect of using a 45S5 bioglass paste and a topical fluoride as protective agents against acidic erosion (resembling acidic beverage softdrinks intake) for enamel surrounding orthodontic brackets.


Sample of 21 freshly extracted sound incisor and premolar teeth was randomly divided into three equal groups: a bioglass group (Bioglass) (NovaMin, 5-mm average particle, NovaMin Technology), a Fluoride group (Fluoride) (Gelato APF Gel, Keystone Industries), and a control group (Control). Orthodontic brackets were bonded to the utilized teeth usingMIP (Moisture Insensitive Primer) and Transbond PLUS color change adhesive. All specimens were challenged by 1% citric acid for 18 min. The top enamel surfaces next to the orthodontic brackets were examined by SEM-EDS. Wilcoxon Signed-Rank test was used to compare the area covered by the 45S5 bioglass paste before/after erosion P < 0.05.


45S5 bioglass paste application resulted in the formation of an interaction layer that significantly resisted erosion challenge P < 0.05. The fluoride and control specimens showed signs of erosion of the enamel next to the orthodontic brackets (P < 0.05).


45S5 bioglass paste can efficiently protect the enamel surfaces next to orthodontic brackets for acidic erosion challenges.


45S5 Bioglass; erosion; orthodontic brackets

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