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Int J Crit Illn Inj Sci. 2019 Jan-Mar;9(1):36-42. doi: 10.4103/IJCIIS.IJCIIS_40_18.

Noninvasive ventilation in acute hypoxic respiratory failure in medical intensive care unit: A study in rural medical college.

Author information

1
Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India.
2
Department of Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India.

Abstract

Introduction:

Noninvasive ventilation (NIV) has emerged as an important tool for the management of acute hypoxic respiratory failure (AHRF) and has been the area of research in the last two decades. In this study, we have tried to find out the outcome of NIV in patients with AHRF.

Materials and Methods:

In this prospective, observational study, all the patients of AHRF requiring NIV were enrolled, and heart rate (HR), respiratory rate (RR), arterial blood gas parameters, and NIV settings at baseline, 1 h, and 4 h were collected. The patients were classified as AHRF with acute respiratory distress syndrome (ARDS) and AHRF without ARDS, which were further classified according to the outcome.

Results:

Among 200 patients admitted in medical intensive care unit (ICU), 50 patients (27 with ARDS and 23 without ARDS) were put on NIV. There was a significant improvement in HR, RR, PaO 2, and inspiratory positive airway pressure after 1 and 4 h and significant improvement at 4 h in expiratory positive airway pressure in all the groups on NIV. Length of ICU stay and hospital stay was less in the nonintubated group. Mortality rate was 25.92% in the intubated group, while it was nil in the nonintubated group.

Conclusion:

NIV found to reduce the endotracheal intubation and mortality, by improving the outcome of the patient.

KEYWORDS:

Acute hypoxic respiratory failure; acute lung injury; acute respiratory distress syndrome; noninvasive ventilation

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