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J Clin Aesthet Dermatol. 2019 Mar;12(3):18-26. Epub 2019 Mar 1.

Facial Lift and Patient Satisfaction Following Treatment with Absorbable Suspension Sutures: 12-Month Data from a Prospective, Masked, Controlled Clinical Study.

Author information

Dr. Nestor is with the Center for Clinical and Cosmetic Research in Aventura, Florida as well as the Department of Dermatology and Cutaneous Surgery and Department of Surgery, Division of Plastic and Reconstructive Surgery at the University of Miami Miller School of Medicine in Miami, Florida.


Objective: We sought to provide short- and long-term data on the duration of results and patient satisfaction achievable with absorbable suspension sutures in the midface. Design: This study included a prospective, masked, controlled 12-week study and 12-month extension study. Setting: This study was conducted in a single center in Aventura, Florida. Participants: Twenty female subjects 41 to 75 years of age with moderate facial skin laxity were included. Measurements: Facial lift was measured using a three-dimensional surface imaging system. Global Aesthetic Improvement Scale (GAIS) scores were reported by subjects and investigators and FACE-Q questionnaires were collected from subjects at Weeks 1, 2, 8, and 12 and Month 12 after treatment. Results: Statistically significant changes in lift were observed through Week 8 (30% of patients had ≥1.5mm of lift [p=0.03]) and mean surface area of lift through Week 12 (patients with ≥1.0mm facial lift had mean surface area of 4.4cm2 [p=0.156]). Improvements in subject and investigator GAIS were observed, along with statistically significant changes in FACE-Q assessments and patient-reported apparent age at each timepoint through 12 months. Subjects tolerated the procedure well, and adverse events were minimal. Conclusion: Absorbable suspension sutures offer an adaptable, safe, minimally invasive approach to tissue lifting and repositioning. The suture provides immediate lift, followed by revolumization and ongoing recontouring that result from the collagen-stimulating properties of the suture, increasing long-term patient satisfaction.


Absorbable suspension sutures; InstaLift; absorbable suture; nonsurgical repositioning; recontouring, revolumization; suspension suture; sutures; tissue repositioning


Conflict of interest statement

FUNDING:Funding for this study was provided by a research grant from Sinclair Pharma. Additionally, funding for medical writing support was provided to Principal Medvantage, LLC by X-Medica, LLC via an educational grant from Sinclair Pharma. DISCLOSURES:Dr. Nestor is a consultant and advisory board member for and has received research grants from Sinclair Pharma, the manufacturer of the study suture. He is also a consultant and advisory board member for Almirall.

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