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Pediatr Infect Dis J. 2019 Jul;38(7):749-751. doi: 10.1097/INF.0000000000002306.

Successful Whole Genome Sequencing-guided Treatment of Mycoplasma hominis Ventriculitis in a Preterm Infant.

Author information

1
From the Department of Pediatrics, Division of Pediatric Infectious Diseases.
2
Department of Pathology and Laboratory Medicine.
3
Department of Pediatrics, Division of Neurosurgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Abstract

We report a case of Mycoplasma hominis ventriculitis in a preterm neonate that was successfully identified with 16S ribosomal RNA sequencing and whole genome sequencing after failure to detect the pathogen with conventional diagnostic methods. The infant required doxycycline with subsequent clearance of the infection and no evidence of drug toxicity.

PMID:
30985508
PMCID:
PMC6565488
[Available on 2020-07-01]
DOI:
10.1097/INF.0000000000002306

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