Format

Send to

Choose Destination
Eur J Nutr. 2019 Apr 13. doi: 10.1007/s00394-019-01964-z. [Epub ahead of print]

Associations between long-term adherence to healthy diet and recurrent depressive symptoms in Whitehall II Study.

Author information

1
Inserm, U1198, University of Montpellier, Ecole Pratique des Hautes Etudes, PSL Research University, Montpellier, 34095, France.
2
Department of Psychiatry and Autism Resources Centre, University Research and Hospital Center of Montpellier, 291 Avenue du Doyen Gaston Giraud, 34295, Montpellier Cedex 5, France.
3
Centre de Recherche en Épidémiologie et Santé des Populations, U1178, INSERM, Paris, France.
4
Department of Epidemiology and Public Health, University College London, London, WC1E 6BT, UK.
5
Department of Behavioural Science and Health, University College London, London, WC1E 6BT, UK.
6
Inserm, U1198, University of Montpellier, Ecole Pratique des Hautes Etudes, PSL Research University, Montpellier, 34095, France. tasnime.akbaraly@inserm.fr.
7
Department of Psychiatry and Autism Resources Centre, University Research and Hospital Center of Montpellier, 291 Avenue du Doyen Gaston Giraud, 34295, Montpellier Cedex 5, France. tasnime.akbaraly@inserm.fr.
8
Department of Epidemiology and Public Health, University College London, London, WC1E 6BT, UK. tasnime.akbaraly@inserm.fr.

Abstract

PURPOSE:

We examined whether long-term adherence to three diet quality scores-the Alternative Healthy Eating Index-2010 (AHEI-2010), Dietary Approach to Stop Hypertension (DASH) and  transformed-Mediterranean Diet Score (tMDS), Alternative Healthy Eating Index-2010 (AHEI-2010) and Dietary Approach to Stop Hypertension (DASH) is associated with the risk of recurrent depressive symptoms.

METHODS:

Analyses were conducted on a sample of 4949 men and women from the Whitehall II study. Diet scores were calculated using data collected from food frequency questionnaires repeated over 11 years of exposure (1991/1993-2002/2004). Recurrence of depressive symptoms was defined when participants reported at least two episodes of depressive symptoms (assessed by Center for Epidemiologic Studies Depression Scale and use of antidepressants) over the four phases of follow-up (2002/04-2015/16).

RESULTS:

After adjustment for potential cofounders, higher scores on AHEI-2010, DASH and tMDS at the end of the exposure period were associated with lower risk of recurrent depressive symptoms over the 13-year follow-up. Repeat measures of dietary history showed that participants who maintained a high AHEI-2010 score over the 11-year exposure period had a 19% (OR 0.81, 95% CI 0.65-1.00) lower odds of recurrent depressive symptoms compared to those who maintained a low AHEI score. Participants whose AHEI-2010 score decreased over time had a 1.34-fold increased odds (95% CI 1.02-1.75) of developing recurrent depressive symptoms compared to those maintaining a high AHEI-2010. No robust associations were observed for long-term tMDS and DASH.

CONCLUSION:

Our findings suggest that long-term adherence to healthy diet defined by Alternative Healthy Eating Index-2010 confers protection against recurrent depressive symptoms.

KEYWORDS:

Alternate Healthy Eating Index-2010; Depressive symptoms; Dietary Approach to Stop Hypertension; Dietary indices; Prospective cohort study; Transformed Mediterranean Diet Score

PMID:
30982178
DOI:
10.1007/s00394-019-01964-z

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center