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J Cancer Res Ther. 2019;15(2):394-397. doi: 10.4103/jcrt.JCRT_725_18.

Magnetic resonance imaging-guided transperineal prostate biopsy.

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Department of Intervention, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.



The purpose of the study is to assess the clinical value of magnetic resonance imaging (MRI)-guided transperineal prostate biopsy in the diagnosis of prostate disease.

Materials and Methods:

The institutional ethics committee approved this study. MRI-guided transperineal prostate biopsy was performed on 78 patients who had presented to our hospital with a prostate-specific antigen level >4 ng/mL or with MRI scans suggesting prostate cancer between January 2015 and August 2017. Written informed consent was obtained from all patients.


Of the 78 patients, pathological diagnosis could not be carried out in one because insufficient prostate tissue was obtained during biopsy. Prostate adenocarcinoma was confirmed in 34 patients, small-cell neuroendocrine carcinoma in 1 patient, prostatic tuberculosis in 1 patient, and benign prostatic hyperplasia in 41 patients. These diagnoses were confirmed by surgical pathology in 31 patients, and all results were consistent with the biopsy pathology, with no false positives. Postoperative urinary tract infection occurred in one patient, and mild postoperative hemorrhage around the prostate gland was seen in 65 patients, without the need for further clinical treatment.


MRI-guided transperineal prostate biopsy is helpful in the diagnosis and treatment of prostatic disease.


Biopsy; magnetic resonance imaging guided; prostate; transperineal

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