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Respir Med. 2019 Apr;150:113-119. doi: 10.1016/j.rmed.2019.02.018. Epub 2019 Feb 25.

Prevalence of and factors associated with adult-onset asthma in different ethnic groups: The HELIUS study.

Author information

1
Department of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: r.aarab@olvg.nl.
2
Department of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
3
Department of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, the Netherlands; Department of Internal Medicine, Division of Infectious Diseases, Academic Medical Centre University of Amsterdam, Amsterdam, the Netherlands.
4
Department of Public Health, Academic Medical Centre, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, Amsterdam, the Netherlands.
5
Departments of Experimental Immunology and of Otorhinolaryngology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
6
Department of Otorhinolaryngology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
7
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, Amsterdam, the Netherlands.

Abstract

Little is known about adult-onset asthma in different ethnic groups. The aim of this study was to examine ethnic differences in the prevalence of adult-onset asthma and factors associated with this phenotype. Cross-sectional data of 23,356 participants of the HELIUS study were used, including Dutch, South-Asian Surinamese, African Surinamese, Moroccan, Turkish and Ghanaian origin participants. Adult-onset asthma was defined as: self-reported asthma symptoms or start of asthma-medication at age ≥18 years combined with a smoking history <10 pack years. The prevalence of adult-onset asthma and its association with potential risk factors were assessed by logistic regression analyses. The adjusted prevalence of adult-onset asthma was higher in the Turkish, Moroccan and South-Asian Surinamese groups (4.9-6.0%) compared to the Dutch, Ghanaian and African Surinamese origin groups (2.4-2.6%). In addition to ethnicity, age, female sex, BMI, and doctors' diagnosis of nasal allergy/hay fever and chronic sinusitis/polyps were independently associated with adult-onset asthma. There are significant differences in the adjusted prevalence of adult-onset asthma among six ethnic groups.

KEYWORDS:

Adult-onset asthma; Epidemiology; Ethnic disparities; Risk factors

PMID:
30961936
DOI:
10.1016/j.rmed.2019.02.018

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