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Chem Commun (Camb). 2019 Apr 18;55(33):4781-4784. doi: 10.1039/c9cc00531e.

A mitochondria targeting artesunate prodrug-loaded nanoparticle exerting anticancer activity via iron-mediated generation of the reactive oxygen species.

Author information

1
Nanshan District Key Lab for Biopolymers and Safety Evaluation, Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, P. R. China. csg@szu.edu.cn.

Abstract

An artesunate anticancer prodrug with a long aliphatic chain N,N'-bis(dodecyl)-l-glutamic diamide was developed into nanoparticle via iron-mediated ROS generation.

PMID:
30957121
DOI:
10.1039/c9cc00531e
[Indexed for MEDLINE]

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