Structure and Function in Drosophila Chromosomes: Visualizing Topological Domains

Daniel R Larson

doi:10.1016/j.molcel.2019.03.017

Structure and Function in Drosophila Chromosomes: Visualizing Topological Domains

Mol Cell. 2019 Apr 4;74(1):3-4. doi: 10.1016/j.molcel.2019.03.017.

Author

Daniel R Larson¹

Affiliation

¹ Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA. Electronic address: dan.larson@nih.gov.

PMID: 30951650
DOI: 10.1016/j.molcel.2019.03.017

Abstract

Cardozo Gizzi et al. (2019) develop a new sequential imaging methodology (Hi-M) for observing chromosome structure in the Drosophila blastoderm and find that topological domains in single nuclei change in response to transcriptional activation.

Published by Elsevier Inc.

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MeSH terms

Animals
Chromosomes
Drosophila / genetics*
Drosophila Proteins / genetics*
Genome
Microscopy

Substances

Drosophila Proteins