The effectiveness of preoperative colon cleansing on post-operative surgical site infection after hip hemiarthroplasty

Eur J Trauma Emerg Surg. 2020 Oct;46(5):1071-1076. doi: 10.1007/s00068-019-01125-1. Epub 2019 Apr 4.

Abstract

Aim: This study aimed to evaluate the effectiveness of prophylactic mechanical bowel preparation in elderly patients undergoing hip hemiarthroplasty in a single training institution over a period of 2 years.

Patients and methods: The study was conducted in a prospective-randomised manner. All patients, who underwent primary hip hemiarthroplasty for femoral neck fracture in our institution between 20 February 2015 and 29 December 2016, were included. B.T. Enema (sodium dihydrogen phosphate + disodium hydrogen phosphate) 135 ml (Yenisehir Laboratory, Ankara, Turkey) was used for colon cleansing.

Results: Ninety-five patients were followed up for at least 1 year after surgery (16.3 ± 4.2 months). Of these, 46 were in the enema group and 49 were in the control group. Demographic and clinical characteristics of patients were similar in both groups (p > 0.05). Infection rates between the two groups were not significantly different (p > 0.05). In addition, ASA, age, sex, presence of diabetes mellitus, duration of surgery, time to surgery, ambulation status and blood count did not have a significant effect on surgical site infections (p > 0.05). However, all infections in the enema group were monobacterial and were successfully treated, whereas two of the four infections in the control group were polymicrobial and could not be successfully treated.

Conclusion: Although preoperative colon cleansing did not reduce the overall incidence of post-operative infections, our study suggested that it may reduce polymicrobial infections after hip hemiarthroplasty. Polymicrobial infections after hip hemiarthroplasty seem to have worse prognosis. Therefore, the effectiveness of preoperative colon cleansing in remediating such infections must be investigated in a larger number of patients.

Keywords: Colon cleansing; Hip fracture; Hip hemiarthroplasty; Hospital care; Infection.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Aged, 80 and over
  • Arthroplasty, Replacement, Hip / methods*
  • Cathartics / administration & dosage*
  • Colon / microbiology*
  • Female
  • Femoral Neck Fractures / surgery*
  • Hemiarthroplasty*
  • Humans
  • Male
  • Preoperative Care*
  • Prospective Studies
  • Surgical Wound Infection / prevention & control*

Substances

  • Cathartics