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Clin Lung Cancer. 2019 May;20(3):e229-e232. doi: 10.1016/j.cllc.2019.02.014. Epub 2019 Feb 27.

Case Report: Temporal Heterogeneity of ALK Activating Mutations in Sequential ALK TKI-Treated Non-Small-Cell Lung Cancer Revealed Using NGS-Based Liquid Biopsy.

Author information

1
Department of Oncology, the Second Affiliated Hospital of Harbin Medical University, Harbin Medical University, Harbin, China.
2
Translational Medicine Research Institute, Geneseeq Technology Inc, Toronto, Ontario, Canada.
3
Translational Medicine Research Institute, Geneseeq Technology Inc, Toronto, Ontario, Canada; School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China.
4
Department of Oncology, the Second Affiliated Hospital of Harbin Medical University, Harbin Medical University, Harbin, China. Electronic address: yangyu13836125585@163.com.

KEYWORDS:

ALK secondary mutation; EML4-ALK; Longitudinal monitoring; Resistance mutation; Target sequencing

PMID:
30948231
DOI:
10.1016/j.cllc.2019.02.014

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