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Neuron. 2019 Apr 3;102(1):6-8. doi: 10.1016/j.neuron.2019.03.016.

Managing Neuronal Ensembles: Somatostatin Interneuron Subpopulations Shape and Protect Cortical Neuronal Ensembles for Learning.

Author information

1
Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
2
Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland. Electronic address: caroni@fmi.ch.

Abstract

Learning is accompanied by temporal compression and sharpening of neuronal firing sequences. In this issue of Neuron, Adler et al. (2019), using a motor skill paradigm and its variant, uncover a dual role for somatostatin interneuron regulation to support ensemble compaction and protection in learning.

KEYWORDS:

VIP interneuron; calcium imaging; dendritic plasticity; motor skill learning; neuronal ensembles; somatostatin interneuron; spine plasticity

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