Format

Send to

Choose Destination
J BUON. 2019 Jan-Feb;24(1):143-149.

Hepatic arterial infusion in liver tumors of unknown, uncertain or unusual primary: single-center experience.

Author information

1
Fourth Department of Medicine, Charles University Medical School Teaching Hospital, Hradec Kralove, Czech Republic.

Abstract

PURPOSE:

The aim of the present study was to analyze a single-center experience with hepatic arterial infusion (HAI) in patients with unknown or uncertain primary or tumors not usually treated with HAI.

METHODS:

A retrospective analysis of 14 patients treated between 1996 and 2003 for liver tumors of unknown, uncertain or unusual primary was performed.

RESULTS:

All patients were treated with HAI combination regimens based on 5-fluorouracil and folinic acid. The response was not evaluable in most patients, predominantly because of only a single course of therapy could be administered and no cases of partial or complete response were noted. The median survival of all patients was 6.6 months (5-year survival 14%).

CONCLUSION:

The present data demonstrate limited efficacy of HAI in patients with liver tumors of unknown, uncertain or unusual primary. HAI should not be offered to these patients.

PMID:
30941963

Supplemental Content

Loading ...
Support Center