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J Clin Neurol. 2019 Apr;15(2):235-242. doi: 10.3988/jcn.2019.15.2.235.

A Multicenter, Randomized Clinical Trial to Assess the Efficacy of a Therapeutic Intervention Program for Caregivers of People with Dementia.

Author information

1
Department of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea.
2
Department of Psychology, Hallym University, Chuncheon, Korea.
3
Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea.
4
Department of Neurology, Keimyung University College of Medicine, Dongsan Medical Center, Daegu, Korea.
5
Department of Neurology, Inha University School of Medicine, Incheon, Korea.
6
Department of Neurology, Bobath Memorial Hospital, Seongnam, Korea.
7
Department of Neurology, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.
8
Department of Psychiatry, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, Korea.
9
Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
10
Department of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea. jjeong@ewha.ac.kr.

Abstract

BACKGROUND AND PURPOSE:

Caregivers experience tremendous social, financial, physical, and psychological burdens in caring for people with dementia. This study aimed to determine the efficacy of a multicomponent therapeutic intervention program for the caregivers of people with dementia (CGPWD) through a multicenter clinical trial: the intervention program-caregivers of people with dementia study.

METHODS:

The 38 caregivers of dementia patients at 8 sites were randomized into 2 groups: treatment (n=19) and control (n=19). The treatment group received the intervention program for 8-10 weeks, including one group session for dementia education and three individual sessions (on cognitive behavioral therapy, coping with stress, and stress management) and single targeted training for daily activities. The Korean version of the Zarit Burden Interview (ZBI-K) and the Geriatric Depression Scale (GDS) were evaluated at pre- and postintervention as primary efficacy measures.

RESULTS:

The treatment group displayed significant improvements in scores on the ZBI-K and GDS. The ZBI-K score at postintervention was significantly reduced in the treatment group compared to that in the control group [6.2-point decrease vs. 3.7-point increase, t(37)=-2.9, p<0.01]. There was a significant difference in the GDS score between the treatment and control groups [2.2-point decrease vs. 1.3-point increase, t(18)=2.5, p<0.05].

CONCLUSIONS:

The findings of this study imply that a multicomponent therapeutic intervention program is effective in reducing the burden experienced by and depression among CGPWD. Further research is warranted to investigate the long-term effects of the intervention program for CGPWD.

KEYWORDS:

caregivers; cognitive behavior therapy; dementia; intervention

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