Send to

Choose Destination
Med Sci (Paris). 2019 Mar;35(3):266-270. doi: 10.1051/medsci/2019034. Epub 2019 Apr 1.

[CRISPR babies: technology and transgression].

[Article in French]

Author information

UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS ; CoReBio PACA, case 901, Parc scientifique de Luminy, 13288 Marseille Cedex 09, France.


Analysing the data recently presented by Jiankui He and assuming that it is authentic shows that the goal of abolishing the expression of CCR5 may have been reached for one of the resulting twins, although this remains to be proven. However, the canonical delta32 mutation has not been achieved. The various preliminary experiments and controls give some confidence that major off-target modifications have not occurred; again, this is difficult to exclude. Clearly, the requirements of perfect technical mastery of the process have not been met, to say nothing of the requirements for complete transparency and full societal approval.


Supplemental Content

Full text links

Icon for EDP Sciences
Loading ...
Support Center