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Cranio. 2019 Mar 31:1-7. doi: 10.1080/08869634.2019.1596054. [Epub ahead of print]

Are certain factors involved in calcium metabolism associated with temporomandibular disorders?

Author information

1
a Dental Research Center , Mashhad University of Medical Sciences , Mashhad , Iran.
2
b Department of Parasitology and Mycology, Faculty of Medicine , Mashhad University of Medical Sciences , Mashhad , Iran.
3
c Metabolic Syndrome Research Center , Mashhad University of Medical Sciences , Mashhad , Iran.
4
d Department of Prosthodontics, Faculty of Dentistry , Shahid Sadoughi University of Medical Sciences , Yazd , Iran.
5
e Private practice , Mashhad , Iran.
6
f Department of Prosthodontics, Faculty of Dentistry , Mashhad University of Medical Sciences , Mashhad , Iran.

Abstract

OBJECTIVE:

The aim of the present study was to investigate whether there is an association between serum concentrations of calcium, phosphate, alkaline phosphatase, parathyroid hormone (PTH), and vitamin D and temporomandibular disorders (TMDs).

METHODS:

In this case-control study, 51 patients with TMDs (28 patients with TMJ clicking, 5 patients with muscular disorders, and 18 osteoarthritis patients) and 29 healthy subjects within the age range of 20-50 years as the control group, were referred to the laboratory for calcium, phosphate, alkaline phosphatase, PTH, and vitamin D (25 OHD) analysis tests. The TMJ status of all participants was examined according to RDC-TMD criteria by a prosthodontist who is an expert in TMDs. The results were analyzed with Fisher's precise test.

RESULTS:

No statistically significant difference was observed between TMD patients and healthy subjects.

CONCLUSION:

Serum concentrations of calcium, phosphate, alkaline phosphatase, PTH, and vitamin D are not associated with TMDs.

KEYWORDS:

Temporomandibular disorders (TMDs); alkaline phosphatase; calcium; parathyroid hormone (PTH); phosphate; vitamin D

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