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Magn Reson Med. 2019 Aug;82(2):732-742. doi: 10.1002/mrm.27732. Epub 2019 Mar 29.

Motion corrected water/fat whole-heart coronary MR angiography with 100% respiratory efficiency.

Author information

1
King's College London, School of Biomedical Engineering and Imaging Sciences, London, United Kingdom.
2
Siemens Healthcare, MR Research Collaborations, Frimley, United Kingdom.
3
Pontificia Universidad Católica de Chile, Escuela de Ingeniería, Santiago, Chile.

Abstract

PURPOSE:

To develop a framework for respiratory motion-corrected 3D whole-heart water/fat coronary MR angiography (CMRA) at 3T with reduced and predictable scan time.

METHODS:

A 3D dual-echo acquisition and respiratory motion-corrected reconstruction framework for water/fat CMRA imaging was developed. The acquisition sequence integrates a 2D dual-echo image navigator (iNAV), enabling 100% respiratory scan efficiency. Respiratory motion estimated from both the 2D iNAVs and the 3D data itself is used to produce nonrigid motion-corrected water/fat CMRA images. A first study to investigate which iNAV (water, fat, in-phase or out-of-phase) provides the best translational motion estimation was performed in 10 healthy subjects. Subsequently, nonrigid motion-corrected water/fat images were compared to a diaphragmatic navigator gated and tracked water/fat CMRA acquisition. Image quality metrics included visible vessel length and vessel sharpness for both the left anterior descending and right coronary arteries.

RESULTS:

Average vessel sharpness achieved with water, fat, in-phase and out-of-phase iNAVs was 33.8%, 29.6%, 32.2%, and 38.5%, respectively. Out-of-phase iNAVs were therefore used for estimating translational respiratory motion for the remainder of the study. No statistically significant differences in vessel length and sharpness (P > 0.01) were observed between the proposed nonrigid motion correction approach and the reference images, although data acquisition was significantly shorter (P < 2.6×10-4 ). Motion correction improved vessel sharpness by 60.4% and vessel length by 47.7%, on average, in water CMRA images in comparison with no motion correction.

CONCLUSION:

The feasibility of a novel motion-corrected water/fat CMRA approach has been demonstrated at 3T, producing images comparable to a reference gated acquisition, but in a shorter and predictable scan time.

KEYWORDS:

coronary MRA; respiratory motion correction; water/fat; whole-heart

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