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Nutrients. 2019 Mar 28;11(4). pii: E725. doi: 10.3390/nu11040725.

The Effects of Dietary Supplements on Asthma and Lung Cancer Risk in Smokers and Non-Smokers: A Review of the Literature.

Author information

1
Menzies Health Institute Queensland, Heart, Mind and Body Research Group, Griffith University, Gold Coast 4222, Australia. naser.alsharairi@gmail.com.

Abstract

Smoking is one of the major global causes of death. Cigarette smoke and secondhand (passive) smoke have been causally related to asthma and lung cancer. Asthma is a potential risk factor for developing lung cancer in both smokers and non-smokers. Prospective studies and randomized control trials (RCTs) of dietary supplements and lung cancer risk in adult smokers and non-smokers have yielded inconsistent results. A few prospective studies have shown that long-term use of high doses of some supplements, such as retinol, β-carotene, B vitamins, and vitamin E, increase lung cancer risk in current and former smokers. Limited evidence from RCTs suggests that vitamin D supplementation is effective in improving lung function and reducing asthma risk in current/former smokers. The relationship between dietary supplements and lung cancer risk has never before been examined in asthmatic smokers and non-smokers. This short review aims to examine the evidence from existing studies for the effects of dietary supplements on asthma/lung cancer risk and mortality in smokers and non-smokers.

KEYWORDS:

asthma; current smokers; dietary supplements; former smokers; lung cancer; non-smokers

PMID:
30925812
PMCID:
PMC6521315
DOI:
10.3390/nu11040725
[Indexed for MEDLINE]
Free PMC Article

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