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SAGE Open Med Case Rep. 2019 Mar 21;7:2050313X19838744. doi: 10.1177/2050313X19838744. eCollection 2019.

Anaphylactic reaction to ethylene oxide in a hemodialysis patient.

Author information

1
Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
2
Department of Renal Diseases and Hypertension, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
3
Divisions of Pulmonary, Critical Care, Sleep Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Abstract

We present the case of a patient who developed a severe systemic allergic reaction during initiation of hemodialysis. The reaction completely resolved by switching the dialysis filter sterilized by ethylene oxide to a steam sterilized filter. Ethylene oxide is used to sterilize heat sensitive medical devices, and although allergic reactions related to ethylene oxide have been reported before, awareness is lacking among providers in the inpatient setting, specifically in the intensive care unit setting.

KEYWORDS:

Ethylene oxide; anaphylaxis; dialyzer; hemodialysis filter; systemic allergy

Conflict of interest statement

Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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