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Cardiol J. 2019 Mar 26. doi: 10.5603/CJ.a2019.0028. [Epub ahead of print]

The effect of Cistus incanus herbal tea supplementation on oxidative stress markers and lipid profile in healthy adults.

Author information

1
Department of Clinical Chemistry; Medical University of Gdansk; Poland. agakuchta@gumed.edu.pl.
2
Department of Pharmaceutical Microbiology; Medical University of Gdansk;Poland.
3
Department of Analytical Chemistry; Medical University of Gdansk; Poland.
4
Department of Clinical Chemistry; Medical University of Gdansk; Poland.
5
1st Department of Cardiology; Medical University of Gdansk; Poland.
6
Department of Therapeutic Drug Monitoring and Pharmacogenetics; Medical University of Gdansk; Poland.

Abstract

BACKGROUND:

Oxidative stress and dyslipidemia play a critical role in the development of cardiovascular disease. Regular intake of polyphenol-rich diets is associated with a reduced risk of cardiovascular diseases.

METHODS:

The present study was a pilot study with 24 healthy volunteers and was designed to determine if a 12-week administration of Cistus incanus herbal tea, containing phenolic acids and flavonoids, reduces cardiovascular risk factors including oxidative stress and dyslipidemia in healthy adults. Phenolic compounds profile and antibacterial activity of Cistus incanus infusion were also measured.

RESULTS:

Herbal infusion led to improvement in lipid profile by increase (D4%, p = 0.033) high-density lipoprotein cholesterol concentration and decrease triglyceride (D14%, p = 0.013) concentrations. In addition, the Cistus incanus diet was associated with decreased serum concentrations of malondialdehyde (D16%, p < 0.01) and advanced oxidation protein products (D18%, p < 0.001).

CONCLUSIONS:

Cistus incanus administration decreases cardiovascular risk factors including oxidative stress and dyslipidemia and this action supports the idea of using Cistus incanus tea on a daily basis as an effective dietary component for prevention of atherosclerotic cardiovascular disease.

KEYWORDS:

Cistus incanus; lipid profile; oxidative stress markers

PMID:
30912576
DOI:
10.5603/CJ.a2019.0028
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