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Acta Psychiatr Scand. 2019 Jun;139(6):548-557. doi: 10.1111/acps.13028. Epub 2019 Apr 8.

Incidence of medically treated depression in Denmark among individuals 15-44 years old: a comprehensive overview based on population registers.

Author information

1
National Center for Register-Based Research, Department of Economics and Business Economics, Aarhus University, Aarhus, Denmark.
2
The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.
3
CIRRAU - Center for Integrated Register-based Research at Aarhus University, Aarhus, Denmark.
4
Department of Depression and Anxiety, Aarhus University Hospital Psychiatry, Aarhus, Denmark.
5
Research Unit for General Practice, Section for General Medicine, Institute of Public Health, Aarhus University, Aarhus, Denmark.

Abstract

OBJECTIVE:

Examine the overall incidence of medically treated depression in Denmark among individuals 15-44 years old, and estimate the 5-year cumulative incidence of psychiatric hospital care among individuals treated first in non-hospital-based care.

METHODS:

We followed all individuals born in Denmark between 1969 and 1998 from age 15 or 2006 (whichever came first) until first depression treatment; death; emigration; or December 31, 2013. Incidence rates were estimated using Poisson regression. Cumulative incidence of hospital care following treatment in non-hospital care was estimated using Kaplan-Meier curves.

RESULTS:

In this sample of 2 014 760 individuals, incidence rates of depression in non-hospital and hospital-based care in 2012-2013 were 6.6 (95% Confidence Interval: 6.5-6.7) per 1000 person-years and 1.5 (95% CI: 1.5-1.6) per 1000 person-years, respectively. Overall, 85-90% of first medical treatment for depression took place outside of psychiatric hospitals, but a quarter (26.3%) of individuals treated for depression received hospital care initially or within 5 years. Incidence of hospital care was higher in women and younger individuals.

CONCLUSIONS:

Most medical treatment for depression in Denmark takes place in non-hospital settings. Women and younger individuals are more likely to receive hospital care both initially and within 5 years after first antidepressant treatment.

KEYWORDS:

antidepressives; depression; epidemiology; general practice; treatment

PMID:
30908590
DOI:
10.1111/acps.13028

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