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J Am Med Inform Assoc. 2019 May 1;26(5):462-478. doi: 10.1093/jamia/ocy185.

Comparison of blockchain platforms: a systematic review and healthcare examples.

Author information

1
UCSD Health Department of Biomedical Informatics, University of California San Diego, La Jolla, California, USA.
2
Department of Mathematics, East Los Angeles College, Monterey Park, California, USA.
3
Division of Health Services Research & Development, VA San Diego Healthcare System, La Jolla, California, USA.

Abstract

OBJECTIVES:

To introduce healthcare or biomedical blockchain applications and their underlying blockchain platforms, compare popular blockchain platforms using a systematic review method, and provide a reference for selection of a suitable blockchain platform given requirements and technical features that are common in healthcare and biomedical research applications.

TARGET AUDIENCE:

Healthcare or clinical informatics researchers and software engineers who would like to learn about the important technical features of different blockchain platforms to design and implement blockchain-based health informatics applications.

SCOPE:

Covered topics include (1) a brief introduction to healthcare or biomedical blockchain applications and the benefits to adopt blockchain; (2) a description of key features of underlying blockchain platforms in healthcare applications; (3) development of a method for systematic review of technology, based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement, to investigate blockchain platforms for healthcare and medicine applications; (4) a review of 21 healthcare-related technical features of 10 popular blockchain platforms; and (5) a discussion of findings and limitations of the review.

KEYWORDS:

PRISMA; blockchain; distributed ledger technology; health and Medicine; systematic review

PMID:
30907419
DOI:
10.1093/jamia/ocy185

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