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Indian J Dent Res. 2019 Jan-Feb;30(1):52-56. doi: 10.4103/ijdr.IJDR_267_17.

Influence of infiltrant application time on the reduction of opaqueness of proximal enamel caries.

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Health Sciences Center, Federal University of Paraiba, Cidade Universitária, 58051-900 João Pessoa, Paraiba, Brazil.
Department of Morphology, Health Science Center, Federal University of Paraiba, Cidade Universitaria, 58051-900 João Pessoa, Paraiba, Brazil.



Infiltrant resins were developed to hamper carious lesion progression and mask the whitish appearance of first evidence of caries.


This study aimed at testing the hypothesis that a long application time of resin infiltrant in proximal enamel caries improves esthetic outcome compared to the commercially recommended time.

Materials and Methods:

Twenty teeth with uncavitated inactive proximal white enamel caries lesions (selected by two calibrated examiners; inter-examiner κ = 0.87) were divided into two groups (experimental and control group; n = 10) that agreed regarding lesion surface area. Lesions were infiltrated following the protocol recommended by the manufacturer (two applications, 3 min application first and another 1 min application later; control) and by the protocol tested in this study (one application of 30 min; experimental). Enamel opaqueness (esthetic outcome) was measured by a calibrated examiner (intra-class coefficient of 0.9) before and after infiltration using fluorescence microscopy.


Reduction of enamel opaqueness was significantly higher in the experimental group (40.0% ± 18.5%) than in the control group (18.6% ± 14.9%) (P = 0.0105, one-tailed t-test; Hedge's g of 1.28, 95% confidence interval of 0.43/2.13, and power of 86%).


It can be concluded that the application time of 30 min provides a greater reduction in opaqueness of proximal enamel lesion compared to the application time recommended by the manufacturer. The high effect size could stimulate patients to comply with the treatment time.


Caries infiltration; dental caries; dental enamel; dental esthetics

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