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Indian J Ophthalmol. 2019 Apr;67(4):563-566. doi: 10.4103/ijo.IJO_801_18.

Ocular coherence tomography angiography features of congenital hypertrophy of retinal pigment epithelium.

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Department of Vitreoretina and Ocular Oncology, Sankara Eye Hospital, Bangalore, Karnataka, India.


Congenital hypertrophy of retinal pigment epithelium (CHRPE) is a benign, pigmented, flat lesion arising from the retinal pigment epithelium (RPE). In this study, we describe optical coherence tomography angiography (OCTA) features of two eyes with solitary CHRPE. We found that the retinal vasculature over CHRPE was normal in both cases. We observed that in solitary CHRPE, segmentation artifacts can interfere in the interpretation of retinal vasculature due to thinning of the outer retina. Visualization of the underlying choroidal vasculature was obscured to some extent by masking effect of the hyperpigmented RPE. The choroidal vasculature was better appreciated on en face OCTA. On OCTA, the retinal and choroidal vasculature associated with CHRPE was found to be normal in our study.


Congenital hypertrophy of retinal pigment epithelium; masking; optical coherence tomography angiography; pigmentation; solitary; unmasking

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