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Crit Rev Anal Chem. 2019 Mar 22:1-25. doi: 10.1080/10408347.2019.1586520. [Epub ahead of print]

The Application of Supercritical Fluid Chromatography in Food Quality and Food Safety: An Overview.

Author information

1
a School of Pharmacy , China Medical University , Shenyang , China.
2
b Department of Pharmacy , National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.
3
c Department of Medical Oncology , National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.

Abstract

Recently, supercritical fluid chromatography (SFC) has attracted considerable attention for their application in food analysis. The use of supercritical CO2 (SC-CO2), as a mobile phase for SFC, with its low viscosity and high molecular diffusiveness, results in shorter analysis time and lower consumption of organic solvents as compared to high-performance liquid chromatography (HPLC). In addition, with recent improvements in its detection system, SFC has shown satisfactory selectivity and sensitivity. Thus, although the composition of food is complex, SFC remains a powerful tool in food analysis with some simple sample pretreatment techniques, such as liquid-liquid extraction, solid-phase extraction, and QuEChERS. Here, we summarize the applications of SFC in food quality and safety from 2012 to 2018, and mainly focus on sample pretreatment strategies and analysis conditions.

KEYWORDS:

Food analysis; pesticide analysis; sample pretreatment; supercritical fluid chromatography (SFC)

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