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Magn Reson Med. 2019 Aug;82(2):825-832. doi: 10.1002/mrm.27736. Epub 2019 Mar 21.

An 8-channel receive array for improved 31 P MRSI of the whole brain at 3T.

Author information

1
Department of Radiology and Nuclear Medicine, Radboud university medical center, Nijmegen, The Netherlands.
2
Department of Geriatric Medicine, Radboud university medical center, Nijmegen, The Netherlands.
3
Radboudumc Alzheimer Center, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, The Netherlands.
4
Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, United Kingdom.
5
Erwin L. Hahn Institute, University Hospital Duisburg-Essen, Essen, Germany.

Abstract

PURPOSE:

To demonstrate a 1 H/31 P whole human brain volume coil configuration for 3 Tesla with separate 31 P transmit and receive components that maintains 1 H MRS performance and delivers optimal 31 P MRSI with 1 H decoupling.

METHODS:

We developed an 8-channel 31 P receive array coil covering the head to be used as an insert for a commercial double-tuned 1 H/31 P birdcage transmit-receive coil. This retains the possibility of using low-power rectangular pulses for 1 H-decoupled 3D 31 P MRSI (nominal resolution 17.6 cm3 ; acquisition duration 13 min) but increases the SNR with the receive sensitivity of 31 P surface coils. The performance of the combined coil setup was evaluated by measuring 1 H and 31 P SNR with and without the 31 P receive array and by assessing the effect of the receive array on the transmit efficiencies of the birdcage coil.

RESULTS:

Compared to the birdcage coil alone, the 31 P insert in combination with the birdcage achieved an average 31 P SNR gain of 1.4 ± 0.4 in a center partition of the brain. The insert did not cause losses in 1 H MRS performance and transmit efficiency, whereas for 31 P approximately 20% more power was needed to achieve the same γB1.

CONCLUSION:

The new coil configuration allows 1 H MRSI and optimal 1 H-decoupled 3D 31 P MRSI, with increased SNR of the human brain without patient repositioning, for clinical and research purposes at 3 Tesla.

KEYWORDS:

1H-decoupling; 3 Tesla; 31P MR spectroscopic imaging; RF array coil; brain

PMID:
30900352
PMCID:
PMC6520216
[Available on 2019-08-01]
DOI:
10.1002/mrm.27736

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