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Elife. 2019 Mar 21;8. pii: e45380. doi: 10.7554/eLife.45380.

Why structure matters.

Author information

1
IST Austria, Klosterneuburg, Austria.
2
Department of Mathematics, University of Vienna, Vienna, Austria.
3
Max F. Perutz Laboratories, University of Vienna, Vienna, Austria.
4
Gregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.

Abstract

Great care is needed when interpreting claims about the genetic basis of human variation based on data from genome-wide association studies.

KEYWORDS:

GWAS; evolutionary biology; genetics; genomics; human; polygenic adaptation; population genetics; population structure; quantitative genetics; selection for human height

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