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Biochim Biophys Acta. 1986 Aug 7;860(1):84-90.

Vitamin E in young and old human red blood cells .

Erratum in

  • Biochim Biophys Acta 1987 Jan 26;896(2):323.

Abstract

Young and old human red blood cells contain about the same amount of alpha-tocopherol, a compound which has previously been shown to be the major lipid-soluble, chain-breaking antioxidant present in such cells. Since red blood cells lose up to ca. 20% of lipid material from their membrane as they age, the alpha-tocopherol/membrane-lipid ratio actually rises with age rather than declining as might have been expected on the basis of the free radical theory of aging. The alpha-tocopherol/arachidonic acid moiety ratios increase in the order: young red blood cells less than old red blood cells less than plasma, which argues against the suggested membrane stabilizing effect of alpha-tocopherol/arachidonic acid moiety complexes.

PMID:
3089279
DOI:
10.1016/0005-2736(86)90501-8
[Indexed for MEDLINE]

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