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Open Med (Wars). 2018 Dec 31;13:456-459. doi: 10.1515/med-2018-0069. eCollection 2018.

Resectable Single Hepatic Epithelioid Hemangioendothelioma in the Left Lobe of the Liver: A Case Report.

Author information

1
Department of Biliary Surgery, West China Hospital, Sichuan University, Chengdu 610041, Chengdu China.
2
Laboratory of Pathology, West China Hospital, Sichuan University, Chengdu 610041, Chengdu China.
3
Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, Chengdu China.

Abstract

Hepatic epithelioid hemangioendothelioma (HEHE) is an extremely rare malignancy of vascular origin. When most patients with HEHE are diagnosed, they have a diffuse nodular phenotype, which is usually unresectable. A single nodular phenotype is found in only a small proportion (13%) of patients, and most are reported to be located in the right lobe of the liver. Although the prognosis of HEHE is considered more favorable than that of other hepatic malignant tumors, the 5-year survival rate is reported to be 64% after treatment. Herein, we present an unusual case of resectable HEHE of a single nodular type in the left lobe of the liver. The patient survived 15 years without recurrence after the multimodal treatment of radical resection and postoperative chemotherapy with thalidomide. The aim of the present study is to emphasize that multimodal treatment of radical resection followed by chemotherapy with thalidomide may achieve a relatively good survival outcome in patients with resectable HEHE of a single nodular type.

KEYWORDS:

Chemotherapy; Early surgery; Hepatic epithelioid hemangioendothelioma; Single nodular

Conflict of interest statement

Conflict of interest Conflict of interests: We declare that we have no any conflict of interests.

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