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Europace. 2019 Mar 18. pii: euz055. doi: 10.1093/europace/euz055. [Epub ahead of print]

EHRA White Paper: knowledge gaps in arrhythmia management-status 2019.

Author information

1
St. Vincenz-Krankenhaus GmbH, Cardiology and Intensive Care Medicine, Am Busdorf 2, 33098 Paderborn, Germany.
2
Working Group Molecular Electrophysiology, University Hospital Magdeburg, Magdeburg, Germany.
3
Department of Cardiology, Fondazione Cardiocentro Ticino, Lugano (Ticino), Switzerland.
4
Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy.
5
Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
6
Department of Cardiology, Hospital Clinic, University of Barcelona, Barcelona, Spain.
7
Department of Cardiology, University Hospital of Geneva, Geneva, Switzerland.
8
St. George's, University of London, Molecular and Clinical Sciences Research Institute, London, UK.
9
Department of Cardiology and Cardiovascular Research Institute Maastricht (CARIM), Maastricht UMC+, Maastricht, The Netherlands.
10
Department of Electrophysiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
11
Department of Cardiology, Aix Marseille Université, CHU la Timone, Marseille, France.
12
University Duisburg-Essen, Institute of Pharmacology, Essen, Germany.
13
Department of Cardiology and Angiology, National Cardiovascular Institute, NUSCH, Bratislava, Slovak Republic.
14
Division of Clinical Electrophysiology, Department of Cardiology, J.W. Goethe University, Frankfurt, Germany.
15
Univ Rennes, CHU Rennes, LTSI-UMR1099, Rennes, France.
16
Department of Cardiology and Intensive Care, Hospital for Internal Medicine Munich South, Munich, Germany.
17
Department of Cardiology, University of Bonn, Bonn, Germany.
18
Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, UK.
19
Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
20
Hospital Universitario La Paz, Arrhythmia and Robotic EP Unit, Madrid, Spain.
21
Department of Physiology, Maastricht University, Maastricht, Netherlands.
22
Cardiology Division, University Hospital Udine, Udine, Italy.
23
Department of Cardiology, Ordensklinikum Linz Elisabethinen, Academic Teaching Hospital, Linz, Austria.
24
Barts Heart Centre, Barts and the London NHS Trust, London, UK.
25
University Heart Center Zurich, Zurich, Switzerland.
26
Department Of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
27
Department of Cardiology, Leiden University Medical Center (Lumc), Leiden, Netherlands.
28
Department Of Cardiology, University Clinical Centre Ljubljana, Ljubljana, Slovenia.
29
Antwerp University and Antwerp University Hospital, Antwerp, Belgium.

Abstract

Clinicians accept that there are many unknowns when we make diagnostic and therapeutic decisions. Acceptance of uncertainty is essential for the pursuit of the profession: bedside decisions must often be made on the basis of incomplete evidence. Over the years, physicians sometimes even do not realize anymore which the fundamental gaps in our knowledge are. As clinical scientists, however, we have to halt and consider what we do not know yet, and how we can move forward addressing those unknowns. The European Heart Rhythm Association (EHRA) believes that scanning the field of arrhythmia / cardiac electrophysiology to identify knowledge gaps which are not yet the subject of organized research, should be undertaken on a regular basis. Such a review (White Paper) should concentrate on research which is feasible, realistic, and clinically relevant, and should not deal with futuristic aspirations. It fits with the EHRA mission that these White Papers should be shared on a global basis in order to foster collaborative and needed research which will ultimately lead to better care for our patients. The present EHRA White Paper summarizes knowledge gaps in the management of atrial fibrillation, ventricular tachycardia/sudden death and heart failure.

KEYWORDS:

Heart failure; Arrhythmia; European Heart Rhythm Association; Fibrillation; Tachycardia; White Paper

PMID:
30882143
DOI:
10.1093/europace/euz055

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