Format

Send to

Choose Destination
Curr Biol. 2019 Apr 1;29(7):1089-1099.e7. doi: 10.1016/j.cub.2019.02.019. Epub 2019 Mar 14.

Neural Evolution of Context-Dependent Fly Song.

Author information

1
Janelia Research Campus of the Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA.
2
Department of Biology, Emory University, Atlanta, GA 30322, USA.
3
Janelia Research Campus of the Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA. Electronic address: sternd@janelia.hhmi.org.

Abstract

It is unclear where in the nervous system evolutionary changes tend to occur. To localize the source of neural evolution that has generated divergent behaviors, we developed a new approach to label and functionally manipulate homologous neurons across Drosophila species. We examined homologous descending neurons that drive courtship song in two species that sing divergent song types and localized relevant evolutionary changes in circuit function downstream of the intrinsic physiology of these descending neurons. This evolutionary change causes different species to produce divergent motor patterns in similar social contexts. Artificial stimulation of these descending neurons drives multiple song types, suggesting that multifunctional properties of song circuits may facilitate rapid evolution of song types.

KEYWORDS:

Drosophila; behavior; courtship song; evolution; neuroscience

PMID:
30880014
DOI:
10.1016/j.cub.2019.02.019
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center