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Rev Prat. 2018 Oct;68(8):886-890.

[Cryoconservation of gametes: how to perform?]

[Article in French; Abstract available in French from the publisher]

Author information

1
Laboratoire de biologie de la reproduction- CECOS, AP-HM, La Conception, Marseille, France. Aix Marseille Univ, CNRS, IRD, Avignon Univ, IMBE UMR 7263, Marseille, France.
2
Laboratoire de biologie de la reproduction- CECOS, CHU Dijon, Dijon, France. Équipe génétique des anomalies du développement, UMR 1231 Inserm/ uB, Dijon, France.
3
Laboratoire de biologie de la reproduction- CECOS, AP-HM, La Conception, Marseille, France. Université de Marseille, Inserm, GMGF UMR S910, Marseille, France.
4
Laboratoire de biologie de la reproduction- CECOS, CHU Dijon, Dijon, France. IMOST, Inserm 1240, faculté de médecine, Clermont-Ferrand, France.

Abstract

in English, French

Cryoconservation of gametes : how to perform ? The patients can preserve their gametes when they are exposed to potential gonadotoxic pathology or treatment. In this context, the French bioethical law clearly states the obligation to inform the patients about the risks for their fertility and the possibilities to cryopreserve their gametes. Regional platforms of fertility preservation allow notably for the coordination of the oncology teams and the CECOS. For the men, sperm freezing is achieved by a slow and controlled temperature protocol. For the women, the oocytes are usually vitrified after hormonal stimulation and ovarian punction. For both, the gametes are cryopreserved in straws and stored in liquid nitrogen until use in assisted reproductive treatment (ART). Each year, the CECOS keeping the gametes interrogates patients on their wish to continue, or not, the cryoconservation. The gametes can only be used in ART by the patients only during their lifetime and with their consent, without alterations related to the duration of storage.

KEYWORDS:

cryoconservation of gametes; fertility

PMID:
30869457

Conflict of interest statement

P. Fauque déclare des liens ponctuels (interventions et invitations lors de congrès) avec Merck Serono, MSD et Ferring. F. Brugnon, M. Paci, J. Perrin et H. Pons-Rejraji déclarent n’avoir aucun lien d’intérêts.

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