Format

Send to

Choose Destination
J Ultrasound. 2019 Sep;22(3):363-370. doi: 10.1007/s40477-019-00361-w. Epub 2019 Mar 12.

Hepatocellular carcinoma tumor thrombus entering the inferior vena cava treated with percutaneous RF ablation: a case report.

Author information

1
Internal Medicine Division, Ostuni Hospital, Ostuni, BR, Italy.
2
Interventional Ultrasound Unit, Tortorella Clinical Hospital, Salerno, Italy.
3
Radiodiagnostic Unit, Ostuni Hospital, Ostuni, BR, Italy.
4
Interventional Radiology Unit, Perrino Hospital, Brindisi, Italy.
5
Anesthesiology and Reanimation Unit, Ostuni Hospital, Ostuni, BR, Italy.
6
Pediatric Gastroenterology Unit, Policlinico Gemelli, Sacred Heart University, Rome, Italy.
7
Internal Medicine Division, Ostuni Hospital, Ostuni, BR, Italy. stefsem@libero.it.

Abstract

PURPOSE:

Hepatocellular carcinoma (HCC) is the most common form of liver cancer. In advanced cancer stages (metastatic disease and/or vascular invasion), the generally accepted standard of care is systemic therapy using sorafenib as first-line treatment and, recently, regorafenib and nivolumab as second-line treatment, but the quality of life and the prognosis of patients remain very poor. Our paper reports a case of US-guided radiofrequency ablation (RFA) of both intraparenchymal HCC and inferior vena cava tumor thrombus.

METHODS:

We treated a patient with HCC associated with tumor thrombus extending into vena cava after failure of sorafenib therapy using US-guided radiofrequency ablation (RFA).

RESULTS:

A good radiological and clinical response was observed in association with excellent tolerability. The patient has been followed up for 15 months from the ablation, is alive, and is in a good clinical condition without evidence of tumor recurrence.

CONCLUSION:

This is the first case in which this minimally invasive percutaneous procedure has been successfully used to treat an HCC thrombus entering the vena cava.

KEYWORDS:

Hepatocellular carcinoma; Locoregional therapy; Sorafenib; Tumor thrombus; US-guided radiofrequency ablation

PMID:
30864004
PMCID:
PMC6704268
[Available on 2020-09-01]
DOI:
10.1007/s40477-019-00361-w

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center